广州医科大学呼吸疾病国家重点实验室 南山学者，特聘教授
中国科学院广州生物医药与健康研究院 特聘研究员
1984年毕业于上海医学院医学系，1992年获得美国印第安纳大学医学院博士，1992-1996年在哈佛医学院从事研究。1997-2001年在美国默克实验室担任资深研究员，是当时最具创新性的腺病毒载体艾滋病疫苗第一发明人。2003年非典疫情过后，全时回国到广州担任中科院广州生物医药与健康研究院创始院长，并联合钟南山院士创建了呼吸疾病国家重点实验室。曾长期在跨国知名药企从事研发与管理，先后担任过英国葛兰素史克、法国赛诺菲巴斯德研发副总裁。2013年起重返祖国科研战线，参与呼吸道病毒及疫苗研究并担任呼吸疾病国家重点实验室常务副主任（2013-2017）。新冠疫情发生早期开展了新冠病毒感染后抗体动态变化的研究（EMI），参与了中检院新冠病毒检测试剂国家参考品的联合研制。领导由和信健康、呼吸疾病国家重点实验室等联合成功研发出15分钟新冠抗体快速诊断试剂盒并于3月11日获得药监局批文。领导由恩宝生物与广东省实验室、呼吸疾病国家重点实验室、中科院联合研发腺病毒载体新冠肺炎疫苗，于7月初获得国家知识产权局2项专利授权，为国内最早获得授权的腺病毒载体新冠疫苗专利，研究成果发表在自然-通讯。

Dr. Chen has been a Professor in State Key Lab of Respiratory Disease, Guangzhou Medical University since 2013. He also serves as a Principal Investigator and was the founding Director General (2004-2008) of Guangzhou Institute of biomedicine and health, Chinese Academy of Sciences. Dr. Chen received a medical degree from Shanghai Medical College in 1984. He obtained a Ph.D. in Biochemistry and Molecular Biology from Indiana University School of Medicine. Dr. Chen completed his postdoctoral training at Dana-Farber Cancer Institute, Harvard Medical School. From 1997-2001, Dr. Chen served as a Senior Research Fellow at Merck Research Laboratories. Dr. Chen has over 100 publications in infectious diseases, vaccine research, and cancer research. His current research is focused on vaccine and antibody research on adenovirus, influenza virus, and emerging viruses. Since the outbreak of SARS-CoV-2, he has investigated antibody response in COVID-19 patients (published in EMI on May 1). He is the inventor of two granted COVID-19 vaccine patents (China Patent Office NIPA).
Publications on COVID-19 (*Senior correspondence):
Feng L, Wang Q, Shan C, Yang C, Feng Y, Wu J, Liu X, Zhou Y, Jiang R, Hu P, Liu X, Zhang F, Li P, Niu X, Liu Y, Zheng X, Luo J, Sun J, Gu Y, Liu B, Xu Y, Li C, Pan W, Zhao J, Ke C, Chen X, Xu T, Zhong N, *Guan S, *Yuan ZM, *Chen L An adenovirus-vectored COVID-19 vaccine confers protection from SARS-COV-2 challenge in rhesus macaques, Nature Communicatons 2020, DOI https://doi.org/10.1038/s41467-020-18077-5
Niu X, Li S, Li P, Pan W, Wang Q, Feng Y, Mo X, Yan Q, Ye X, , Luo J, Qu L, Weber D, Byrne-Steele M, Wang Z, Yu F, Li F, Myers R, Lotze M, Zhong Z, *Han J, *Chen L. Longitudinal analysis of T and B cell receptor repertoire transcripts reveal dynamic immune response in COVID-19 patients. Front Immunol. 2020 doi: 10.3389/fimmu.2020.582010
SUN B, Feng Y, Mo X, Zheng P, Wang Q, Li P, Peng P, Liu X, Chen Z, Huang H, Zhang F, Luo W, Niu X, Hu P, Wang L, Pe ng H, Huang Z, Feng L, Li F, Zhang F, *Li F, *Zhong N, *CHEN L Kinetics of SARS-CoV-2 specific IgM and IgG responses in COVID-19 patients. Emerg Microbes Infect. 2020 May 1:1-36. doi: 10.1080/22221751.2020.1762515.